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Licensed Unlicensed Requires Authentication Published by De Gruyter December 19, 2015

Polyol-based biodegradable polyesters: a short review

  • Weng Hong Tham , Mat Uzir Wahit EMAIL logo , Mohammed Rafiq Abdul Kadir , Tuck Whye Wong and Onn Hassan

Abstract

Catalyst-free thermal polyesterification has recently emerged as a potential strategy for designing biodegradable thermoset polymers, particularly polyol-based polyesters for biomedical applications. These thermoset polyesters are synthesized through polycondensation of polyol and polyacid without the presence of catalyst or solvents. The mechanical properties, degradation rates, crystallinity, hydrophilicity, and biocompatibility can be controlled by adjusting the monomer feed ratios and curing conditions. These polyesters often degrade via surface erosion that allows the polymers to maintain structural integrity throughout hydrolysis. Additionally, polyol-based polyesters demonstrated good biocompatibility as non-toxic catalysts and/or solvents involved in the reaction, and the monomers used are endogenous to human metabolism which can be resorbed and metabolized in various physiological pathways. This review summarizes the polyol-based biodegradable polyesters that were synthesized by catalyst-free polyesterification.


Corresponding author: Mat Uzir Wahit, Enhanced Polymer Research Group (EnPRO), Faculty of Chemical Engineering, Department of Polymer Engineering, Universiti Teknologi Malaysia (UTM), 81300 Johor Bahru, Johor, Malaysia; and Centre for Composites (CfC), Institute of Vehicle System and Engineering (IVeSE), Universiti Teknologi Malaysia (UTM), 81300 Johor Bahru, Johor, Malaysia

Acknowledgments

The authors wish to acknowledge the Exploratory Research Grant Scheme (ERGS) Vote No: 4L031 and Prototype Research Grant Scheme (PRGS) Vote No: 4L608 by Universiti Teknologi Malaysia from the Ministry of Science, Technology and Innovation (MOSTI).

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Received: 2015-5-30
Accepted: 2015-10-15
Published Online: 2015-12-19
Published in Print: 2016-4-1

©2016 by De Gruyter

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