Summary
Dihydroneopterin has recently been shown to either promote or decrease formation of free radicals or radicalmediated reactions, depending on the conditions. We report here the scavenging activity of dihydroneopterin on nitrogen centered radicals. Diphenylpicrylhydrazyl (DPPH) and tl. e radical cation of 2,2' -azino-di-[3- ethylbenzthiazoline sulphonate] (ABTS) were used. Dihydroneopterin showed scavenging properties against either compound. In the case of DPPH radical scavenging by dihydroneopterin was comparable with trolox. In the ABTS system, dihydroneopterin had an even better capacity of radical scavenging as compared to trolox .
© 2013 by Walter de Gruyter GmbH & Co.
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