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Congenital anomalies, prematurity, and low birth weight rates in relation to nuclear power plant proximity1)

  • Tania Mangones , Paul Visintainer and Heather L. Brumberg EMAIL logo

Abstract

Objective: The objective of this study was to determine whether maternal residential proximity to a nuclear reactor is associated with prevalence of certain birth defects.

Study design: The New York State Vital Statistics and Congenital Malformations Registry data (1992–2001) were analyzed for five Hudson Valley counties in a 20-mile radius from the Indian Point nuclear reactor (Buchanan, NY, USA). Four zones of 5-mile increments were used to categorize proximity to the reactor. Data included congenital anomalies, low birth weight, and prematurity.

Result: Over the 10-year period, 702 malformations in 666 children were identified from a birth population of 328,124, yielding a regional rate of 2.1 major malformations per 1000 births. The prevalence of defects, low birth weight, and prematurity were not related to proximity to the nuclear power plant.

Conclusion: These data did not substantiate an association between maternal proximity to the reactor and certain birth defects and provide baseline data for comparison in the event of a nuclear accident.


Corresponding author: Heather L. Brumberg, MD, MPH, Division of Newborn Medicine, Department of Pediatrics, New York Medical College, Maria Fareri Children’s Hospital at Westchester Medical Center, Valhalla, NY 10595, USA, Tel.: +1-914-493-8491, Fax: +1-914-493-1005

This work was supported in part by New York State Empire Clinical Research Investigator Program Grant # 5957001H. We thank the New York State Vital Statistics and Congenital Malformations Registry staff for providing data and Denton Brosius, PhD, for aid with the mapping of the region. We also thank Dr. Edmund G. LaGamma for helpful discussions and Dr. Joshua C. Brumberg, Dr. Yoko Nomura, Dr. Sergio Golombek, and Dr. Stephan F. Brumberg for comments on the manuscript.

  1. 1)

    The results were presented in preliminary form at the New York State Perinatal Society Annual meeting in 2007.

References

[1] American Academy of Pediatrics Committee on Environmental Health. Ionizing radiation. In: Etzel RA, editor. Pediatric environmental health. 3rd ed. Elk Grove Village, IL: American Academy of Pediatrics; 2012:421–37.Search in Google Scholar

[2] Backgrounder on emergency preparedness at nuclear power plants. Available at: http://www.nrc.gov/reading-rm/doc-collections/fact-sheets/emerg-plan-prep-nuc-power-bg.html. Accessed 19 February, 2012.Search in Google Scholar

[3] Baker PJ, Hoel DG. Metaanalysis of standardized incidence and mortality rates of childhood leukaemia in promimity to nuclear facilities. Eur J Cancer Care. 2007;16:355–63.10.1111/j.1365-2354.2007.00679.xSearch in Google Scholar PubMed

[4] Boneva RS, Botto LD, Moore CA, Yang Q, Correa A, Erickson JD. Mortality associated with congenital heart defects in the United States: trends and racial disparities, 1979–1997. Circulation. 2001;103:2376–8.10.1161/01.CIR.103.19.2376Search in Google Scholar PubMed

[5] Brent RL. Saving lives and changing family histories: appropriate counseling of pregnant women and men and women of reproductive age, concerning the risk of diagnostic radiation exposures during and before pregnancy. Am J Obstet Gynecol. 2009;200:4–24.10.1016/j.ajog.2008.06.032Search in Google Scholar PubMed

[6] Demographic data. Available at: http://quickfacts.census.gov/qfd/states/36/36119.html (Westchester County, New York); http://quickfacts.census.gov/qfd/states/00000.html (USA). Both accessed 6 July, 2012.Search in Google Scholar

[7] Desantis M, Cesari E, Nobili E, Straface G, Cavaliere AF, Caruso A. Radiation effects on development. Birth Defects Res (Part C). 2007;81:177–82.10.1002/bdrc.20099Search in Google Scholar PubMed

[8] Emergency planning. Available at: http://keepingsafe.westchestergov.com/emergency-planning. Accessed 26 May, 2011.Search in Google Scholar

[9] Fairlie I. Commentary: childhood cancer near nuclear power stations. Environ Health. 2009;8:43.10.1186/1476-069X-8-43Search in Google Scholar PubMed PubMed Central

[10] Hall P, Adami HO, Trichopoulos D, Pedersen NL, Lagiou P, Ekbom A, et al. Effect of low doses of ionising radiation in infancy on cognitive function in adulthood: swedish population based cohort study. Br Med J. 2004;328:19.10.1136/bmj.328.7430.19Search in Google Scholar PubMed PubMed Central

[11] Harjulehto T, Aro T, Rita H, Rytömaa T, Saxén L. The accident at Chernobyl and outcome of pregnancy in Finland. Br Med J. 1989;298:995–7.10.1136/bmj.298.6679.995Search in Google Scholar PubMed PubMed Central

[12] Hoffman W. Fallout from the Chernobyl nuclear disaster and congenital malformations in Europe. Arch Environ Health. 2001;56:478–84.10.1080/00039890109602895Search in Google Scholar PubMed

[13] Japan – earthquake, tsunami and nuclear crisis. New York Times 8/29/11; 2011. Available at: http://topics.nytimes.com/top/news/international/countriesandterritories/japan/index.html. Accessed 23 September, 2011.Search in Google Scholar

[14] Kinlen L. Childhood leukaemia, nuclear sites, and population mixing. Br J Cancer. 2011;104:12–8.10.1038/sj.bjc.6605982Search in Google Scholar PubMed PubMed Central

[15] Lambert J, Cornell R. A study of vital rates near a nuclear reactor. Arch Environ Health. 1980;35:235–9.10.1080/00039896.1980.10667498Search in Google Scholar PubMed

[16] List of Power Reactor Units. Available at: http://www.nrc.gov/reactors/operating/list-power-reactor-units.html. Accessed 3 February, 2011.Search in Google Scholar

[17] Location of nuclear power plants. Available at: http://www.nrc.gov/info-finder/region-state/. Accessed 6 July, 2012.Search in Google Scholar

[18] Lupo PJ, Symanski E, Chan W, Mitchell LE, Waller DK, Canfield MA, et al. Differences in exposure assignment between conception and delivery: the impact of maternal mobility. Paediatr Perinat Epidemiol. 2010;24:200–8.10.1111/j.1365-3016.2010.01096.xSearch in Google Scholar

[19] Mangano J, Gould J, Sternglass E, Sherman J, Brown J, McDonnell W. Infant death and childhood cancer reductions after nuclear plant closings in the United States. Arch Environ Health. 2002;57:23–31.10.1080/00039890209602913Search in Google Scholar

[20] Mangano J, Sherman J, Chang C, Dave A, Feinberg E, Frimer M. Elevated childhood cancer incidence prxomate to U.S. nuclear power plants. Arch Environ Health. 2003;58:74–83.10.3200/AEOH.58.2.74-82Search in Google Scholar

[21] Mangano JJ, Gould JM, Sternglass EJ, Sherman JD, McDonnell W. An unexpected rise in strontium-90 in US deciduous teeth in the 1990s. Sci Total Environ. 2003;317:37–51.10.1016/S0048-9697(03)00439-XSearch in Google Scholar

[22] Miller RW. Delayed effects of external exposure: a brief history. Radiat Res. 1995;144:160–9.10.2307/3579255Search in Google Scholar

[23] New York State Department of Health Congenital Malformations Registry. Statistical summary of children born 1998–2001 and diagnosed through 2003. New York: New York State Department of Health; 2007. Available from URL: http://www.health.state.ny.us/diseases/congenital_malformations/docs/98report.pdf. Accessed 25 May, 2011.Search in Google Scholar

[24] Nuclear Power in the USA. Available at: http://www.world-nuclear.org/info/inf41.html. Accessed 19 May, 2011.Search in Google Scholar

[25] Pearce A. Recommended nuclear decay data. NPL Report IR6, January. Middlesex, UK: National Physical Laboratory; 2008. Available at: http://publications.npl.co.uk/npl_web/pdf/ir6.pdf. Accessed 13 September, 2012.Search in Google Scholar

[26] Prasad KN, Cole WC, Hasse GM. Health risks of low dose ionizing radiation in humans: a review. Exp Biol Med. 2004;229:378–82.10.1177/153537020422900505Search in Google Scholar PubMed

[27] Radiation disasters and children. American Academy of Pediatrics Committee on Environmental Health. Pediatrics. 2003;111:1455–66.Search in Google Scholar

[28] Selemon LD, Ceritoglu C, Ratnanather JT, Wang L, Harms MP, Aldridge K, et al. Distinct abnormalities of the primate prefrontal cortex caused by ionizing radiation in early or midgestation. J Comp Neurol. 2012. DOI: 10.1002/cne.23217 [Epub ahead of print].10.1002/cne.23217Search in Google Scholar PubMed PubMed Central

[29] Sever LE, Gilbert ES, Hessol NA, McIntyre JM. A case-control study of congential malformations and occupational exposure to low-level ionizing radiation. Am J Epidemiol. 1988;127:226–42.10.1093/oxfordjournals.aje.a114799Search in Google Scholar PubMed

[30] Socio-economic status of communities with nuclear power plants. Available at: http://quickfacts.census.gov/qfd/index.html. Accessed 6 July, 2012.Search in Google Scholar

[31] Sutherland BM, Bennet PV, Sidorkina O, Laval J. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation. Proc Natl Acad Sci USA. 2000;97:103–8.10.1073/pnas.97.1.103Search in Google Scholar PubMed PubMed Central

[32] Tunstall H, Pickett K, Johnsen S. Residential mobility in the UK during pregnancy and infancy: are pregnant women, new mothers and infants ‘unhealthy migrants’? Soc Sci Med. 2010;71:786–98.10.1016/j.socscimed.2010.04.013Search in Google Scholar PubMed

[33] US Nuclear Regulatory Commission’s effluents database for nuclear power plants. Available at: http://www.reirs.com/effluent/EDB_Main.asp. Accessed 13 September, 2012.Search in Google Scholar

[34] Watson GE, Lorimore SA, Macdonald DA, Wright EG. Chromosomal instability in unirradiated cells induced in vivo by a bystander effect of ionizing radiation. Cancer Res. 2000;60:5608–11.Search in Google Scholar

[35] Zhu JL, Knudsen LE, Andersen A-MN, Hjollund NH, Olsen J. Laboratory work and pregnancy outcomes: a study within the national birth cohort in Denmark. Occup Environ Med. 2006;63:53–8.10.1136/oem.2005.021204Search in Google Scholar PubMed PubMed Central

The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2012-3-29
Accepted: 2012-11-16
Published Online: 2012-12-21
Published in Print: 2013-07-01

©2013 by Walter de Gruyter Berlin Boston

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