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Licensed Unlicensed Requires Authentication Published by De Gruyter September 11, 2014

From cerebral salt wasting to diabetes insipidus with adipsia: case report of a child with craniopharyngioma

  • Veena Raghunathan EMAIL logo , Maninder Singh Dhaliwal , Aditya Gupta and Ganesh Jevalikar

Abstract

Craniopharyngioma is associated with a wide and interesting variety of sodium states both by itself and following surgical resection. These are often challenging to diagnose, especially given their dynamic nature during the perioperative course. We present the case of a boy with craniopharyngioma who had hyponatremia due to cerebral salt wasting preoperatively, developed diabetes insipidus (DI) intraoperatively and proceeded to develop hypernatremia with adipsic DI.

Conclusion: Cerebral salt wasting is a rare presenting feature of craniopharyngioma. Postoperative DI can be associated with thirst abnormalities including adipsia due to hypothalamic damage; careful monitoring and a high index of suspicion are required for its detection. Adipsic DI is a difficult condition to manage; hence a conservative surgical approach is suggested.


Corresponding author: Dr Veena Raghunathan, Associate Consultant, Pediatric Critical Care, Medanta, The Medicity, Sector 38, Gurgaon, Haryana 122001, India, Phone: +91 9871221112, E-mail:

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Received: 2014-5-28
Accepted: 2014-8-14
Published Online: 2014-9-11
Published in Print: 2015-3-1

©2015 by De Gruyter

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