Abstract
A simple and rapid method for the analysis of parathion in biological samples is presented. The method consists of the extraction of parathion from blood samples by headspace solid-phase micro-extraction (SPME), followed by capillary gas chromatography and mass spectrometry detection. The recoveries in the blood samples after addition of ammonium sulphate and sulphuric acid were between 85 % and 89% compared to samples prepared in water. Linearity was established over a concentration range of 0.1–5 μg/g blood with acceptable coefficients of correlation and limits of detection reached 0.02–0.05 μg/g. The time for an analysis is 57 minutes for one sample, including the extraction step. In conclusion, HS-SPME in combination with GC/MS is an effective method for the determination and quantification of parathion-ethyl and parathion-methyl in biological material.
Copyright © 1999 by Walter de Gruyter GmbH & Co. KG
