Non-Conventional Synthesis: Bioactive Heterocycles

Published by De Gruyter 2024

Non-Conventional Synthesis

Bioactive Heterocycles

Edited by: György Keglevich and Bubun Banerjee

Volume 1 in the series Green Bioactive Heterocycles

https://doi.org/10.1515/9783110980189

Overview
Contents

About this book

Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds.

THE SERIES: GREEN BIOACTIVE HETEROCYCLES
Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.

Discusses untraditional synthesis methods for producing bioactive heterocycles.

Methods explored include the use of microwave, ultrasound, mechanochemistry, photochemistry, biocatalysis, click chemistry, and more.

Author / Editor information

Prof. György Keglevich developed a P-heterocyclic research in the subject of ring enlargement of five-membered P-heterocycles and on the utilization of the products obtained. He elaborated the synthesis of a number of families of compounds. Bridged P-heterocycles, precursors of low-coordinated fragments, were synthesized and utilized in phosphorylations. The study on the synthesis and reactivity of aromatic phosphorus forms another relevant part of his research. Additional research interests for Keglevich include Diels-Alder reactions, low-coordinated P-fragments, phosphine transition metal complexes, selective reductions, phosphine-boranes, azacrown ethers with phosphonoalkyl side-chains and selective reductions. Mechanisms and theoretical aspects are also of his interest. Recently, he has turned towards environmentally friendly syntheses. Environmentally friendly chemistry (green chemistry) forms new aspects of his research. It means MW chemistry, the synergism of MW and phase transfer catalysis, ionic liquids, the development of new catalysts and monitoring reactions by in situ methods. He also took part in industrial projects, such as the synthesis of pharmaceutical intermediates and products.　He is the author or co-author of more than 700 publications (the majority of which appeared in international journals).

Dr. Bubun Banerjee received his Ph.D. degree from Visva-Bharati University, Santiniketan, West Bengal, India. He has nearly nine years of experience in the field of research related to green and sustainable developments. Presently he is working as an assistant professor of chemistry at the Department of Chemistry, Akal University, Talwandi Sabo, Bathinda, Punjab, India. Dr. Banerjee published more than 100 research articles in the internationally renowned journals and authored fifteen book chapters; he also co-edited eleven books and guest edited eleven different special thematic issues of different journals.

Topics

Frontmatter Publicly Available Download PDF	I
Preface Publicly Available Download PDF	V
Foreword Publicly Available Download PDF	VII
A brief professional profile of Prof. Anil Kumar Singh Publicly Available Download PDF	XIII
Contents Publicly Available Download PDF	XV
List of contributors Publicly Available Download PDF	XIX
Chapter 1 Microwave-assisted catalyst-free synthesis of bioactive heterocycles Ali Bodaghi, Ali Ramazani and Zeinab Rafiee Requires Authentication Unlicensed Licensed Download PDF	1
Chapter 2. Microwave-assisted synthesis of N-heterocycles Chetna Ameta Dharmendra, Yogeshwari Vyas, Purnima Chaubisa, Abhilasha Jain and Suresh C. Ameta Requires Authentication Unlicensed Licensed Download PDF	33
Chapter 3. Microwave-assisted synthesis of O,S-heterocycles Rajib Sarkar and Chhanda Mukhopadhyay Requires Authentication Unlicensed Licensed Download PDF	69
Chapter 4. Ultrasound-assisted synthesis of N-heterocycles Yadavalli Venkata Durga Nageswar, Katla Ramesh and Katla Rakhi Requires Authentication Unlicensed Licensed Download PDF	95
Chapter 5. Ultrasound-assisted synthesis of O,S-heterocycles Garima Ameta, Rakshit Ameta, Seema Kothari and Suresh C. Ameta Requires Authentication Unlicensed Licensed Download PDF	129
Chapter 6. Ultrasound-assisted synthesis of bioactive 1,2,3-triazoles via click reactions Bubun Banerjee, Aditi Sharma, Anu Priya, Manmeet Kaur and Arvind Singh Requires Authentication Unlicensed Licensed Download PDF	151
Chapter 7. Photoirradiated synthesis of bioactive heterocycles Prabhakar Chetti, Vipin Kumar and V. Jayathirtha Rao Requires Authentication Unlicensed Licensed Download PDF	173
Chapter 8. Synthesis of heterocycles through electrolysis Poulami Hota, Prasenjit Das, Rajjakfur Rahaman and Dilip K. Maiti Requires Authentication Unlicensed Licensed Download PDF	209
Chapter 9. Flow synthesis of oxygen and nitrogen heterocycles Moumita Saha and Asish R. Das Requires Authentication Unlicensed Licensed Download PDF	261
Chapter 10. Ball-milling-promoted synthesis of bioactive heterocycles Sabir Ahammed, Sandipan Ghosal and Brindaban C. Ranu Requires Authentication Unlicensed Licensed Download PDF	287
Chapter 11. Synthesis of bioactive heterocycles via click reaction Sabbasani Rajasekhara Reddy, Neelima D. Tangellamudi, Bhulakshmi Sathi, Sridhar P. and Adinarayana Doddi Requires Authentication Unlicensed Licensed Download PDF	307
Chapter 12. Synthesis of bioactive heterocycles by nanocatalysis Prasenjit Das, Poulami Hota, Rajjakfur Rahaman and Dilip K. Maiti Requires Authentication Unlicensed Licensed Download PDF	337
Chapter 13. Enantioselective metal-catalyzed domino reactions in the total synthesis of bioactive heterocycles Hélène Pellissier Requires Authentication Unlicensed Licensed Download PDF	375
Chapter 14. Synthesis of pharmacologically significant pentathiepins: a journey from harsh to mild conditions Lukas M. Jacobsen, Roberto Tallarita, Siva S. M. Bandaru and Carola Schulzke Requires Authentication Unlicensed Licensed Download PDF	403
Chapter 15. Developments in the synthesis of ring phosphine oxides György Keglevich Requires Authentication Unlicensed Licensed Download PDF	467
Chapter 16. Total synthesis of bioactive heterocyclic scaffolds via Pauson Khand reaction Sabbasani Rajasekhara Reddy, Sathi Bhulakshmi and Sanjivani Pal Requires Authentication Unlicensed Licensed Download PDF	489
Chapter 17. Nonconventional approaches in drug discovery Shashi Kiran Misra and Kamla Pathak Requires Authentication Unlicensed Licensed Download PDF	517
Index Requires Authentication Unlicensed Licensed Download PDF	551

(Deutsch)

Language: English
Publisher: De Gruyter
Audience: Researchers, industry professionals, and students in chemistry, industrial chemistry, and green chemistry.
Pages
- Front matter: 22
- Main content: 559
Illustrations
- Illustrations: 694
- Coloured Illustrations: 164
- Tables: 10
- Coloured Tables: 2
Keywords: Microwave Assisted Synthesis; Biocatalysis; Photochemistry; Click Chemistry; Electrosynthesis; Electrochemistry; Mechanochemistry; Drug Discovery

eBook

Published: November 6, 2023
ISBN: 9783110980189

Hardcover

Published: November 6, 2023
ISBN: 9783110992267