Abstract
Aims: Clinical follow-up of possible fetal complications associated with maternal parvovirus B19 infection is usually recommended during the 2–3 months after primary infection.
Results: A case of late intrauterine fetal death associated with at least 5 months of maternal parvovirus B19 viremia and in the presence of B19 IgG and IgM is described.
Conclusions: The time of clinical and laboratory follow-up after maternal parvovirus B19 infection may need to be revised if prolonged viremia is more common than previously described.
References
1 Corcoran A, BP Mahon, P McParland, A Davoren, S Doyle: Ex vivo cytokine responses against parvovirus B19 antigens in previously infected pregnant women. J Med Virol70 (2003) 475Search in Google Scholar
2 Jordan JA, D Huff, JA DeLoia: Placental cellular immune response in women infected with human parvovirus B19 during pregnancy. Clin Diagn Lab Immmunol8 (2001) 288Search in Google Scholar
3 Koch WC, JH Harger, B Barnstein B, SP Adler: Serologic and virologic evidence for frequent intrauterine transmission of human parvovirus B19 with a primary maternal infection during pregnancy. Pediatr Infect Dis J17 (1998) 489Search in Google Scholar
4 Miller E, CK Fairley, BJ Cohen, C Seng: Immediate and long-term outcome of human parvovirus B19 infection in pregnancy. Br J Obstet Gynaecol105 (1998) 174Search in Google Scholar
5 Nonoue T, K Kusuhara, T Hara: Human fetal infection with parvovirus B19: maternal infection time in gestation, viral persistence and fetal prognosis. Pediatr Infect Dis J21 (2002) 1133Search in Google Scholar
6 O'Malley A, C Barry-Kinsella, C Hughes, P Kelehan, D Devaney, E Mooney, J Gillan: Parvovirus infects cardiac myocytes in hydrops fetalis. Pediatr Dev Pathol6 (2003) 414Search in Google Scholar
7 Skjoldebrand L, T Tolfvenstam, N Papadogiannakis, B Wahren, K Broliden, M Nyman: Parvovirus B19 infection: association with third-trimester intrauterine fetal death. Br J Obstet Gynaecol107 (2000) 476Search in Google Scholar
8 Söderlund M, R von Essen, J Haapasaari, U Kiistala, O Kiviluoto, K Hedman: Persistence of parvovirus B19 DNA in synovial membranes of young patients with and without chronic arthropathy. Lancet349 (1997) 1063Search in Google Scholar
9 Tolfvenstam T, N Papadogiannakis, O Norbeck, K Petersson, K Broliden: Frequency of human parvovirus B19 infection in intrauterine fetal death. Lancet357 (2001) 1494Search in Google Scholar
©2005 by Walter de Gruyter Berlin New York
