An aqueous solution with doubled ion concentration of simulated body fluid (2.0SBF) was prepared. In order to impart hydroxyapatite formation ability to polylactic acid (PLA) matrixes, the PLA fabric cloth and foam were immersed in 2.0SBF and the pH value was increased. By this treatment, apatite nuclei were precipitated on the PLA matrixes. By immersing in physiological SBF, hydroxyapatite layer was formed on the surface of the PLA matrixes and hydroxyapatite formation ability was successfully performed.