Research progress on the correlation between platelet aggregation and tumor progression
Yuyu Chen1, Jialong Yuan2, Faqing Tang1, Qinglin Liu1, Hongjun Huang1, Huan Liu1 and Hao Liu1
1Department of Clinical Laboratory, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine and 2Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan Province, PR China
Corresponding Author: Yuyu Chen, Department of Clinical Laboratory, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, No. 283 Tongzipo Road, Changsha 410013, Hunan Province, PR China. e-mail: yyucn@hotmail.com
Summary. Platelets are generally considered as the main functional unit of the coagulation system. However, more and more studies have confirmed that platelets also have an important relationship with tumor progression. Tumor cells can utilize platelets to promote their own infiltration and hematogenous metastasis, and platelets are activated and aggregated in this process. Therefore, platelet aggregation may be a concomitant marker of tumor progression. This is of great significance for predicting tumor metastasis before timely treatments. Histol Histopathol 39, 145-152 (2024)
Key words: Platelet, Aggregation, Tumor progression, Metastasis, Growth, Prediction, Molecular mechanism
DOI: 10.14670/HH-18-646
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ŠThe Author(s) 2024. Open Access. This article is licensed under a Creative Commons CC-BY International License. |
