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Vol. 31 No. 10 (2019): Vol 31 Issue 10

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Synthesis and Spectral Studies of Some Bioactive Transition Metal Complexes of [bis-2-(4-Fluorophenyl)prop-2-enaln]ethane-1,2-diamine

https://doi.org/10.14233/ajchem.2019.22049
Jagvir Singh
Department of Chemistry, Atma Ram Sanatan Dharma College (University of Delhi), New Delhi-110021, India
https://orcid.org/0000-0001-7493-8243
Anuradha
Department of Zoology, Raghuveer Singh Government P.G. College, Lalitpur-284403, India
Pradeep Kumar
Department of Chemistry, D.A.V. (P.G.) College, Budhana-251309, India
Mordhwaj
Center of Biomedical Research (ACBR), North Campus, University of Delhi, New Delhi-110007, India
Ravi Kumar
Department of Chemistry, Om Parkash Jogender Singh University, Churu-331303, India

Corresponding Author(s) : Jagvir Singh

singhjagvir0143@gmail.com

Asian Journal of Chemistry, Vol. 31 No. 10 (2019): Vol 31 Issue 10

Abstract

Co(II), Ni(II) and Cu(II) metal complexes of a novel Schiff base ligand (SBL) derived from condensation of 2-(4-fluorophenyl)prop-2-enaln and ethane-1,2-diamine were synthesized. All the complexes were characterized by elemental analyses, IR, UV-visible spectroscopy, magnetic susceptibility and conductance measurements and 1H NMR. From the elemental analysis data, 1:1 [M]:[ligand] metal chloride complexes are formed having the general composition [M(SBL)Cl2] and [Cu(SBL)] Cl2, [where M = Co(II), Ni(II) and SBL= {bis-2-(4-fluorophenyl)prop-2-enaln}ethane-1,2-diamine]. The result showed that the ligand is coordinated to the metal ions in a neutral tetradentate manner with ON donor sites and the nature of metal-ligand bonding can range from covalent to ionic. Antimicrobial activities of the newly synthesized chemical compounds were evaluated against Staphylococcus aureus (ATCC 25923), Staphylococcus aureus (ATCC 3160), Cabdida albicans (ATCC 227) and Staphylococcus cereviscae (ATCC 361) species and found that metal complexes exhibited more antimicrobial properties so they are more potential and significant than the ligand.

Keywords

Schiff base ligands Metal complexes Spectral study Biological study
Singh, J., Anuradha, ., Kumar, P., Mordhwaj, ., & Kumar, R. (2019). Synthesis and Spectral Studies of Some Bioactive Transition Metal Complexes of [bis-2-(4-Fluorophenyl)prop-2-enaln]ethane-1,2-diamine. Asian Journal of Chemistry, 31(10), 2357–2360. https://doi.org/10.14233/ajchem.2019.22049
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