Skip to main content
SpringerLink
Log in

Gingival enlargement in acromegaly

  • Published:
Endocrine Aims and scope Submit manuscript

Abstract

In this study, we investigated gingival enlargement in patients with acromegaly as a component of the disease. Eleven patients (5 males, 6 females) were evaluated. Diagnosis was confirmed with typical clinical features and laboratory. Oral examinations were carried out by the same periodontist. During the examination, plaque index, gingival index, probing pocket depths, and gingival enlargement values were evaluated. Duration of the disease was between 0.2 and 13 yr. Seven patients had pituitary macroadenomas and four had microadenomas during their initial diagnosis. Only one patient was newly diagnosed. The other patients had previously undergone surgery. Gingival enlargement was found in eight patients. Seven patients with gingival enlargement also had prognathism, and one patient had prognathism associated with gingival enlargement. These findings demonstrate that acromegaly that results in overgrowth in various organs should be considered one of the causes of gingival enlargement.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ben-Shlomo, A. and Melmed, S. (2001). Endocrinol. Metab. Clin. North Am. 30, 565–583.

    Article  PubMed  CAS  Google Scholar 

  2. Alexander, L., Appleton, E. M., Hall, R., Ross, W. M., and Wilkinson, R. (1980). Clin. Endocrinol. 12, 71–79.

    CAS  Google Scholar 

  3. Grisoli, F., Leclercq, T., Jaquet, P., Guibout, M., Winteler, J. P., Hassoun, J., and Vincentelli, F. (1985). Surg. Neurol. 23, 513–519.

    Article  PubMed  CAS  Google Scholar 

  4. Thorner, M. O., Vance, M. L., Laws, E. R., Horvath, E., and Kovacs, K. (1998). In: Williams textbook of endocrinology. Wilson, J. D., Foster, D. W., Kronenberg, H. M., and Larsen, P. R. (eds.). W.B. Saunders: Philadelphia.

    Google Scholar 

  5. Clemmons, D. R., Van Wyk, J. J., Ridgway, E. C., Kliman, B., Kjellberg, R. N., and Underwood, L. E. (1979). N. Engl. J. Med. 301, 1138–1142.

    Article  PubMed  CAS  Google Scholar 

  6. Grunstein, R. R., Ho, K. Y., and Sullivan, C. E. (1991). Ann. Intern. Med. 115, 527–532.

    PubMed  CAS  Google Scholar 

  7. Brightman, V. J. (1984). In: Burket’s oral medicine. Lynch, M. A. (ed.). JB Lippincott: Philadelphia.

    Google Scholar 

  8. Syrjanen, S. M. and Syrjanen, K. J. (1979). Proc. Finn. Dent. Soc. 75, 95–98.

    PubMed  CAS  Google Scholar 

  9. Daley, T. D., Wysocki, G. P., and Day, C. (1986). Oral Surg. Oral Med. Oral Pathol. 62, 417–421.1

    Article  PubMed  CAS  Google Scholar 

  10. Lucas, R. M., Howell, L. P., and Wall, B. A. (1985). J. Periodontol. 56, 211–215.

    PubMed  CAS  Google Scholar 

  11. Ferguson, M. M., Stephen, K. W., Dagg, J. H., and Hunter, I. P. (1978). J. Dent. 6, 201–206.

    Article  PubMed  CAS  Google Scholar 

  12. Witkop, C. J. Jr. (1971). Birth Defects Orig. Artic. Ser. 7, 210–221.

    PubMed  Google Scholar 

  13. Melmed, S. (1990). N. Engl. J. Med. 322, 966–977.

    Article  PubMed  CAS  Google Scholar 

  14. Vontobel, F. (1973). Helv. Paediatr. Acta 28, 401–411.

    PubMed  CAS  Google Scholar 

  15. Schmidt, B. L., Pogrel, M. A., Perrott, D. H., and Regezi, J. A. (1995). J. Periodontol. 66, 811–816.

    PubMed  CAS  Google Scholar 

  16. Barkan, A. L., Beitins, I. Z., and Kelech, R. P. (1988). J. Clin. Endocrinol. Metab. 67, 69–73.

    PubMed  CAS  Google Scholar 

  17. Lamberts, S. W., Uitterlinden, P., and Verleun, T. (1987). J. Clin. Invest. 17, 703–710.

    Google Scholar 

  18. Verde, G. G., Santi, I., Chiodini, P., Cozzi, R., Dallabonzana, D., Oppizzi, G., and Luizzi, A. (1986). J. Clin. Endocrinol. Metab. 63, 1406–1410.

    Article  PubMed  CAS  Google Scholar 

  19. Fermin, A. and Carranza, J. R. (1996). In: Clinical periodontology, Fermin, A. and Carranza, J. R. (eds.). W.B. Saunders: Philadelphia.

    Google Scholar 

  20. Marshall, R. I. and Bartold, P. M. (1998). Oral Dis. 4, 130–51.

    Article  PubMed  CAS  Google Scholar 

  21. Thomason, J. M., Kelly, P. J., and Seymour, R. A. (1996). J. Clin. Periodontol. 23, 367–371.

    Article  PubMed  CAS  Google Scholar 

  22. Nishikawa, S., Nagata, T., Morisaki, I., Oka, T., and Ishida, H. (1996). J. Periodontol. 67, 463–471.

    PubMed  CAS  Google Scholar 

  23. Nabbaro, J. D. (1987). Clin. Endocrinol. 26, 481–512.

    Google Scholar 

  24. Akarsu, E., Akcay, G., Canatan, H., Coskun, U., Capoglu, I., and Unuvar, N. (2000). J. Clin. Invest. 23, 28.

    Google Scholar 

  25. Ship, J. A. (1999). Physiol. Behav. 66, 209–215.

    Article  PubMed  CAS  Google Scholar 

  26. Lie, T., Hoof, I., and Gjerdet, N. R. (1987). J. Clin. Periodontol. 14, 149–155.

    Article  PubMed  CAS  Google Scholar 

  27. Silness, J. and Löe, H. (1964). Acta Odontol. Scand. 24, 121–135.

    Google Scholar 

  28. Löe, H. and Silness, J. (1963). Acta Odontol. Scand. 21, 533–551.

    PubMed  Google Scholar 

  29. Pernu, H., Oikarinen, K., Hietanen, J., and Knuuttila, M. (1989). J. Oral Pathol. Med. 18, 422–425.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Endocrinology, Atatürk University Medical Faculty, Turkey

    I. Çapoglu & N. Ünüvar

  2. Department of Biochemistry and Anatomy, Atatürk University Dentistry Faculty, Erzurum, Turkey

    H. Aksoy

  3. Department of Oral Diagnosis, Atatürk University Dentistry Faculty, Erzurum, Turkey

    A. B. Yilmaz

  4. Department of Anatomy, Atatürk University Dentistry Faculty, Erzurum, Turkey

    H. Yesilyurt

  5. Department of Periodontology, Atatürk University Dentistry Faculty, Erzurum, Turkey

    R. Orbak

Authors
  1. I. Çapoglu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. B. Yilmaz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Ünüvar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Orbak
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Aksoy
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. H. Yesilyurt
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to N. Ünüvar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Çapoglu, I., Yilmaz, A.B., Ünüvar, N. et al. Gingival enlargement in acromegaly. Endocr 18, 207–210 (2002). https://doi.org/10.1385/ENDO:18:3:207

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1385/ENDO:18:3:207

Key Words

Search

Navigation