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CT perfusion cerebral blood flow imaging in neurological critical care

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Abstract

Computed tomography (CT) perfusion imaging is a technique for the measurement of cerebral blood flow, cerebral blood volume, and time-to-peak or mean transit time. The technique involves the administration of a single-bolus dose of iodinated contrast material, followed by spiral CT imaging during the passage of the contrast bolus through the cerebral vasculature. CT perfusion is a fast and inexpensive brain imaging modality for use in the management of patients with various neurological disorders, ranging from acute stroke to subarachnoid hemorrhage. This article reviews the technique of CT perfusion and presents several illustrative cases in which this imaging modality was used effectively in the critical care of patients with neurological disorders.

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  1. Department of Neurosurgery and Toshiba Stroke Research Center, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York

    Mark R. Harrigan, Jody Leonardo, Kevin J. Gibbons, Lee R. Guterman & L. Nelson Hopkins

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Harrigan, M.R., Leonardo, J., Gibbons, K.J. et al. CT perfusion cerebral blood flow imaging in neurological critical care. Neurocrit Care 2, 352–366 (2005). https://doi.org/10.1385/NCC:2:3:352

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