Skip to main content
Log in

Feruloyl esterase

A key enzyme in biomass degradation

  • Review Article
  • Published:
Applied Biochemistry and Biotechnology Aims and scope Submit manuscript

Abstract

Feruloyl esterase forms a part of the enzyme complex that acts collectively and synergistically to completely hydrolyze xylan to its monomers. The enzyme has found potential uses in a wide variety of applications of interest to the agrifood and pharmaceutical industries. This review describes the enzymology of feruloyl esterases involved in xylan degradation. The occurrence of feruloyl esterases in various microorganisms and their physiochemical properties are presented. The nature of the enzyme substrates and products, the role of synergistic interactions with xylanases and other accessory enzymes, as well as the sequence-structure relating to the reaction mechanism are emphasized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Saha, B. C. (2003), J. Ind. Microbiol. Biotechnol. 30, 279–291.

    Article  CAS  Google Scholar 

  2. Wyman, C. E. (1994), Bioresour. Technol. 50, 3–16.

    Article  CAS  Google Scholar 

  3. Keller, F. A., Hamilton, J. E., and Nguyen, Q. A. (2003), Appl. Biochem. Biotechnol. 105–108, 27–41.

    Article  Google Scholar 

  4. Williamson, G., Kroon, P. A., and Faulds, C. B. (1998), Microbiology 144, 2011–2023.

    CAS  Google Scholar 

  5. deVries, R. P., vanKuyk, P. A., Kester, H. C. M., and Visser, J. (2002), Biochem. J. 363, 377–386.

    Article  CAS  Google Scholar 

  6. Faulds, C. B. and Williamson, G. (1999), J. Sci. Food Agric. 79, 450–452.

    Article  CAS  Google Scholar 

  7. Harris, P. J. and Hartley, R. D. (1980), Biochem. Sys. Ecol. 8, 153–160.

    Article  CAS  Google Scholar 

  8. Harris, P. J. and Hartley, R. D. (1976), Nature 259, 508–510.

    Article  CAS  Google Scholar 

  9. Ishii, T., Hiroi, T., and Thomas, J. R. (1990), Phytochemistry 29, 1999–2003.

    Article  CAS  Google Scholar 

  10. Nordkvist, E., Salomonsson, A.-C., and Aman, P. (1984), J. Sci. Food Agric. 35, 657–661.

    Article  CAS  Google Scholar 

  11. Bartolome, B., Faulds, C. B., and Williamson, G. (1997), J. Cereal Sci. 25, 285–288.

    Article  CAS  Google Scholar 

  12. Smith, M. M. and Hartley, R. D. (1983), Carbohydr. Res. 118, 65–80.

    Article  CAS  Google Scholar 

  13. Rhodes, D. I., Sadek, M., and Stone, B. A. (2002), J. Cereal Sci. 36, 67–81.

    Article  CAS  Google Scholar 

  14. Saulnier, L. and Thibault, J.-F. (1999), J. Sci. Food Agric. 79, 396–402.

    Article  CAS  Google Scholar 

  15. Ralet, M.-C., Faulds, C. B., Williamson, G., and Thibault, J.-F. (1994), Carbohydr. Res. 263, 257–269.

    Article  CAS  Google Scholar 

  16. Colquhoun, I. J., Ralet, M.-C., Thibault, J.-F., Faulds, C. B., and Williamson, G. (1994), Carbohydr. Res. 263, 243–256.

    Article  CAS  Google Scholar 

  17. Hatfield, R. D., Ralph, J., and Grabber, J. H. (1999), J. Sci. Food Agric. 79, 403–407.

    Article  CAS  Google Scholar 

  18. Iiyama, K., Lam, T. B. T., and Stone, B. A. (1990), Phytochemistry 29, 733–737.

    Article  CAS  Google Scholar 

  19. Scalbert, A., Monties, B., Lallemand, J.-Y., Guittet, E., and Rolando, C. (1985), Phytochemistry 24, 1359–1362.

    Article  CAS  Google Scholar 

  20. Ralph, J., Grabber, J. H., and Hatfield, R. D. (1995), Carbohydr. Res. 275, 167–178.

    Article  CAS  Google Scholar 

  21. Iiyama, K., Lam, T. B.-T., and Stone, B. A. (1994), Plant Physiol. 104, 315–320.

    CAS  Google Scholar 

  22. Oudgenoeg, G., Dirksen, E., Ingemann, S., Hilhorst, R., Cruppen, H., Boeriu, C. G., Piersma, S. R., et al. (2002), J. Biol. Chem. 277, 21,332–21,340.

    Article  CAS  Google Scholar 

  23. Boeriu, C. G., Oudgenoeg, G., Spekking, W. T., Berendsen, L. B. J. M., Vancon, L., Boumans, H., Gruppen, H., van Berkel, W. J. H., Laane, C., and Voragen, A. G. J. (2004), J. Agric. Food Chem. 52, 6633–6639.

    Article  CAS  Google Scholar 

  24. Fry, S. C., Willis, S. C., and Paterson, A. E. J. (2000), Planta 211, 679–692.

    Article  CAS  Google Scholar 

  25. Rouau, X., Cheynier, V., Surget, A., Gloux, D., Barron, C., Meudec, E., Louis-Montero, J., and Criton, M. (2003), Phytochemistry 63, 899–903.

    Article  CAS  Google Scholar 

  26. Kato, Y. and Nevins, D. J. (1985), Carbohydr. Res. 137, 139–150.

    Article  CAS  Google Scholar 

  27. Smith, B. G. and Harris, P. J. (2001), Phytochemistry 56, 513–519.

    Article  CAS  Google Scholar 

  28. Mueller-Harvey, I. and Hartley, R. D. (1986), Carbohydr. Res. 148, 71–85.

    Article  CAS  Google Scholar 

  29. Ishii, T. and Hiroi, T. (1990), Carbohydr. Res. 196, 175–183.

    Article  CAS  Google Scholar 

  30. Kato, A., Azuma, J.-I., and Koshijima, T. (1987), Agric. Biol. Chem. 51, 1691–1693.

    CAS  Google Scholar 

  31. Kroon, P. A., Faulds, C. B., Brezillon, C., and Williamson, G. (1997), Eur. J. Biochem. 248, 245–251.

    Article  CAS  Google Scholar 

  32. Fry, S. C. (1982), Biochem. J. 203, 493–504.

    CAS  Google Scholar 

  33. Andreasen, M. F., Christensen, L. P., Meyer, A. S., and Hansen, A. (2000), J. Cereal Sci. 31, 303–307.

    Article  CAS  Google Scholar 

  34. Kroon, P. A., Garcia-Conesa, M. T., Fillingham, I. J., Hazlewood, G. P., and Williamson, G. (1999), J. Sci. Food Agric. 79, 428–434.

    Article  CAS  Google Scholar 

  35. Bunzel, M., Ralph, J., Marita, J. M., Hatfield, R. D., and Steinhart, H. (2001), J. Sci. Food Agric. 81, 653–660.

    Article  CAS  Google Scholar 

  36. Grabber, J. H., Hatfield, R. D., and Ralph, J. (1998), J. Sci. Food Agric. 77, 193–200.

    Article  CAS  Google Scholar 

  37. Grabber, J. H., Hatfield, R. D., Ralph, J., Zon, J., and Amrhein, N. (1995), Phytochemistry 40, 1077–1082.

    Article  CAS  Google Scholar 

  38. Figueroa-Espinoza, M. C. and Rouau, X. (1998), Cereal Chem. 75, 259–265.

    CAS  Google Scholar 

  39. Bunzel, M., Ralph, J., Funk, C., and Steinhart, H. (2005), Tetrahedron Lett. 46, 5845–5850.

    Article  CAS  Google Scholar 

  40. Funk, C., Ralph, J., Steinhart, H., and Bunzel, M. (2005), Phytochemistry 66, 363–371.

    Article  CAS  Google Scholar 

  41. Hatfield, R. D. and Ralph, J. (1999), J. Sci. Food Agric. 79, 425–427.

    Article  CAS  Google Scholar 

  42. Crepin, V. F., Faulds, C. B., and Connerton, I. F. (2003), Biochem. J. 370, 417–427.

    Article  CAS  Google Scholar 

  43. Crepin, V. F., Faulds, C. B., and Connerton, I. F. (2004), Appl. Microbiol. Biotechnol. 63, 647–652.

    Article  CAS  Google Scholar 

  44. MacKenzie, C. R. and Bilous, D. (1988), Appl. Environ. Microbiol. 54, 1170–1173.

    CAS  Google Scholar 

  45. Faulds, C. B. and Williamson, G. (1991), J. Gen. Microbiol. 137, 2339–2345.

    CAS  Google Scholar 

  46. Garcia, B. L., Ball, A. S., Rodriguez, J., Perez-Leblic, M. I., Arias, M. E., and Patino-Copa, J. L. (1998), Appl. Microbiol. Biotechnol. 50, 213–218.

    Article  CAS  Google Scholar 

  47. Faulds, C. B. and Williamson, G. (1993), Biotechnol. Appl. Biochem. 17, 349–359.

    CAS  Google Scholar 

  48. Faulds, C. B. and Williamson, G. (1994), Microbiology 140, 779–787.

    CAS  Google Scholar 

  49. de Vries, R. P., Michelsen, B., Poulsen, C. H., Kroon, P. A., van den Heuvel, R. H. H., Faulds, C. B., Williamson, G., van den Hombergh, J. P. T. W., and Visser, J. (1997), Appl. Environ. Microbiol. 63, 4638–4644.

    Google Scholar 

  50. Juge, N., Williamson, G., Puigserver, A., Cummings, N. J., Connerton, I. F., and Faulds, C. B. (2001), FEMS Yeast Res. 1, 127–132.

    Article  CAS  Google Scholar 

  51. Tenkanen, M., Schuseil, J., Puls, J., and Poutanen, K. (1991), J. Biotechnol. 1, 69–84.

    Article  Google Scholar 

  52. Koseki, T., Furuse, S., Iwano, K. and Matsuzawa, H. (1998), Biosci. Biotechnol. Biochem. 62, 2032–2034.

    Article  CAS  Google Scholar 

  53. Fontes, C. M. G. A., Hazlewood, G. P., Morag, E., Hall, J., Hirst, B. H., and Gilbert, H. J. (1995), Biochem. J. 307, 151–158.

    CAS  Google Scholar 

  54. Grepinet, O., Chebrou, M.-C., and Beguin, P. (1988), J. Bacteriol. 170, 4582–4588.

    CAS  Google Scholar 

  55. Xie, H., Gilbert, H. J., Charnock, S. J., et al. (2001), Biochemistry 40, 9167–9176.

    Article  CAS  Google Scholar 

  56. Blum, D. L., Kataeva, I. A., Li, X.-L., and Ljungdahl, L. G. (2000), J. Bacteriol. 182, 1346–1351.

    Article  CAS  Google Scholar 

  57. Donaghy, J. A., Bronnenmeier, K., Soto-Kelly, P. F., and McKay, A. M. (2000), J. Appl. Microbiol. 88, 458–466.

    Article  CAS  Google Scholar 

  58. McSweeney, C. S., Dulieu, A., and Bunch, R. (1998), Anaerobe 4, 57–65.

    Article  CAS  Google Scholar 

  59. Borneman, W. S., Hartley, R. D., Morrison, W. H., and Akin, D. E. (1990), Appl. Microbiol. Biotechnol. 33, 345–351.

    Article  CAS  Google Scholar 

  60. Borneman, W.S., Ljungdahl, L. G., Hartley, R. D., and Akin, D. E. (1992), Appl. Environ. Microbiol. 58, 3762–3766.

    CAS  Google Scholar 

  61. Borneman, W. S., Ljungdahl, L. G., Hartley, R. D., and Akin, D. E. (1991), Appl. Environ. Microbiol. 57, 2337–2344.

    CAS  Google Scholar 

  62. Dalrymple, B. P., Swadling, Y., Cybinski, D. H., and Xue, G.-P. (1996), FEMS Microbiol. Lett. 143, 115–120.

    Article  Google Scholar 

  63. Aurilia, V., Martin, J. C., McCrae, S. I., Scott, K. P., Rincon, M. T., and Flint, H. J. (2000), Microbiology 146, 1391–1397.

    CAS  Google Scholar 

  64. Fillingham, I. J., Kroon, P. A., Williamson, G., Gilbert, H. J., and Hazlewood, G. P. (1999), Biochem. J. 343, 215–224.

    Article  CAS  Google Scholar 

  65. van Peij, N. N. M. E., Gielkens, M. M. C., de Vries, R. P., Visser, J., and de Vries, R. P., Visser, J., and de Graaff, L. H. (1998), Appl. Environ. Microbiol. 64, 3615–3619.

    Google Scholar 

  66. van Peij, N. N. M. E., Visser, J., and de Graaff, L. H. (1998), Mol. Microbiol. 27, 131–142.

    Article  Google Scholar 

  67. de Vries, R. P., Visser, J., and de Graaff, L. H. (1999), Res. Microbiol. 150, 281–285.

    Article  Google Scholar 

  68. Faulds, C. B. and Williamson, G. (1999), J. Sci. Food Agric. 79, 393–395.

    Article  CAS  Google Scholar 

  69. de Vries, R. P. and Visser, J. (1999), Appl. Environ. Microbiol. 65, 5500–5503.

    Google Scholar 

  70. Dalrymple, B. P. and Swadling, Y. (1997), Microbiology 143, 1203–1210.

    Article  CAS  Google Scholar 

  71. Bartolome, B., Faulds, C. B., Kroon, P. A., Waldron, K., Gilbert, H. J., Hazlewood, G., and Williamson, G. (1997), Appl. Environ. Microbiol. 63, 208–212.

    CAS  Google Scholar 

  72. Ferreira, L. M., Wood, T. M., Williamson, G., et al. (1993), Biochem. J. 294, 349–355.

    CAS  Google Scholar 

  73. Faulds, C. B., Ralet, M.-C., Williamson, G., Hazlewood, G. P., and Gilbert, H. J. (1995), Biochim. Biophys. Acta 1243, 265–269.

    Google Scholar 

  74. Kroon, P. A., Williamson, G., Fish, N. M., Archer, D. B., and Belshaw, N. J. (2000), Eur. J. Biochem. 267, 6740–6752.

    Article  CAS  Google Scholar 

  75. Donaghy, J. and McKay, A. M. (1997), J. Appl. Microbiol. 83, 718–726.

    Article  CAS  Google Scholar 

  76. Faulds, C. B. and Williamson, G. (1995), Appl. Microbiol. Biotechnol. 43, 1082–1087.

    Article  CAS  Google Scholar 

  77. Yu, P., Maens, D. D., McKinnon, J. J., Racz, V. J., and Christensen, D. A. (2002), J. Agric. Food Chem. 50, 1625–1630.

    Article  CAS  Google Scholar 

  78. Yu, P., McKinnon, J., Maenz, D.D., Olkowski, A. A., Racz, V. J., and Christensen, D. A. (2003), J. Agric. Food Chem. 51, 218–223.

    Article  CAS  Google Scholar 

  79. Faulds, C. B., Zanichelli, D., Crepin, V. F., Connerton, I. F., Juge, N., Bhat, M. K., and Waldron, K. W. (2003), J. Cereal Sci., 38, 281–288.

    Article  CAS  Google Scholar 

  80. Vardakou, M., Katapodis, P., Topakas, E., Kekos, D., Macris, B. J., and Christako-poulos, P. (2004), Innovative Food Sci. Emerging Technol. 5, 107–112.

    Article  CAS  Google Scholar 

  81. de Vries, R. P., Kester, H. C. M., Poulsen, C. H., Benen, J. A. E., and Visser, J. (2000), Carbohydr. Res. 327, 401–410.

    Article  Google Scholar 

  82. Kroon, P. A. and Williamson, G. (1996), Biotechnol. Appl. Biochem. 23, 263–267.

    CAS  Google Scholar 

  83. Garcia-Conesa, M.-T., Crepin, V. F., Goldson, A. J., Williamson, G., Cummings, N. J., Connerton, I. F., Faulds, C. B., and Kroon, P. A. (2004), J. Biotechnol. 108, 227–241.

    Article  CAS  Google Scholar 

  84. Crepin, V. F., Faulds, C. B., and Connerton, I. F. (2003), Protein Exp. Purif. 29, 176–184.

    CAS  Google Scholar 

  85. Schubot, F. D., Kataeva, I. A., Blum, D. L., Shah, A. K., Ljungdahl, L. C., Rose, J. P., and Wang, B.-C. (2001), Biochemistry 40, 12,524–12,532.

    Article  CAS  Google Scholar 

  86. Prates, J. A. M., Tarbouriech, N., Charmock, S. J., Fontes, C. M. G. A., Ferreira, L. M. A., and Davies, G. J. (2001), Structure 9, 1183–1190.

    Article  CAS  Google Scholar 

  87. Hermoso, J. A., Sanz-Aparicio, J., Molina, R., Juge, N., Gonzalez, R., and Faulds, C. B. (2004), J. Mol. Biol. 338, 495–506.

    Article  CAS  Google Scholar 

  88. McAuley, K. E., Svendsen, A., Patkar, S. A., and Wilson, K. S. (2004), Acta Crystallogr. D 60, 878–887.

    Article  CAS  Google Scholar 

  89. Faulds, C. B., Molina, R., Gonzalez, R., Husband, F., Juge, N., Sanz-Aparicio, J., and Hermoso, J. A. (2005), FEBS J. 272, 4362–4371.

    Article  CAS  Google Scholar 

  90. Carter, P. and Wells, J. A. (1988), Nature 332, 564–568.

    Article  CAS  Google Scholar 

  91. Brady, L., Brzozowski, A. M., Derewenda, Z. S. et al. (1990), Nature 343, 767–770.

    Article  CAS  Google Scholar 

  92. Grochulski, P., Li, Y., Schrag, J. D., and Cygler, M. (1994), Protein Sci. 3, 82–91.

    Article  CAS  Google Scholar 

  93. Wong, D. W. S. (1995), Food Enzymes: Structure and Mechanism, Chapman & Hall, New York, pp. 125–211.

    Google Scholar 

  94. Ailwan, F. O., Kroon, P. A., Faulds, C. B., Pickersgill, R., and Williamson, G. (1999), J. Sci. Food Agric. 79, 457–459.

    Article  Google Scholar 

  95. Andersen, A., Svendsen, A., Vind, J., Lassen, S. F., Hjort, C., Borch, K., and Patkar, S. A. (2002), Colloids Surf. B Biointerfaces 26, 47–55.

    Article  CAS  Google Scholar 

  96. Daggett, V., Schroder, S., and Kollman, P. (1991), J. Am. Chem. Soc. 113, 8926–8935.

    Article  CAS  Google Scholar 

  97. Warshel, A. and Russel, S. (1986), J. Am. Chem. Soc. 108, 6569–6579.

    Article  CAS  Google Scholar 

  98. Warshel, A., Naray-Szabo, G., Sussman, F., and Hwang, J.-K. (1989), Biochemistry 28, 3629–3637.

    Article  CAS  Google Scholar 

  99. Topakas, E., Christakopoulos, P., and Faulds, C. B. (2005), J. Biotechnol. 115, 355–366.

    Article  CAS  Google Scholar 

  100. Schwimmer, S. (1981), Source Book of Enzymology, Avi Publishing, Westport, CT, pp. 581–592.

    Google Scholar 

  101. Jariwalla, R. J. (2001), Drugs Exp. Clin. Res. 27, 17–26.

    CAS  Google Scholar 

  102. Mathew, S. and Abraham, T. E. (2004), Crit. Rev. Biotechnol. 24(2–3), 59–83.

    Article  CAS  Google Scholar 

  103. Georget, D. M. R., Ng, A., Smith, A. C., and Waldron, K. W. (1999), J. Sci. Food Agric. 79, 481–483.

    Article  CAS  Google Scholar 

  104. Lesage-Meessen, L., Stentelaire, C., Lomascolo, A., Couteau, D., Asther, M., Moukha, S., Record, E., Sigoillot, J.-C., and Asther, M. (1999), J. Sci. Food Agric. 79, 487–490.

    Article  CAS  Google Scholar 

  105. Gasson, M. J., Kitamura, Y., McLauchlan, W. R., Narbad, A., Parr, A. J., Parsons, E. L. H., Payne, J., et al. (1998), J. Biol. Chem. 273, 4163–4170.

    Article  CAS  Google Scholar 

  106. Mathew, S. and Abraham, T. E. (2005), Enzyme Microb. Technol. 36, 565–570.

    Article  CAS  Google Scholar 

  107. Saija, A., Tomaino, A., Cascio, R. L., Trombetta, D., Proteggente, A., Pasquale, A. D., Uccella, N., et al. (1999), J. Sci. Food Agric. 79, 476–480.

    Article  CAS  Google Scholar 

  108. Kennedy, J. F., Methacanon, P., and Lloyd, L. L. (1999), J. Sci. Food Agric. 79, 464–470.

    Article  CAS  Google Scholar 

  109. Topakas, E., Stamatis, H., Biely, P., and Christakopoulos, P. (2004), Appl. Microbiol. Biotechnol. 63, 686–690.

    Article  CAS  Google Scholar 

  110. Topakas, E., Stamatis, H., Biely, P., Kekos, D., Macris, B. J., and Christakopoulos, P. (2003), J. Biotechnol. 102, 33–44.

    Article  CAS  Google Scholar 

  111. Topakas, E., Stamatis, H., Mastihubova, M., Biely, P., Kekos, D., Macris, B. J., and Christakopoulos, P. (2003), Enzyme Microb. Technol. 33, 729–737.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wong, D.W.S. Feruloyl esterase. Appl Biochem Biotechnol 133, 87–112 (2006). https://doi.org/10.1385/ABAB:133:2:87

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1385/ABAB:133:2:87

Index Entries

Navigation