Abstract
The analysis of gene differential expression is complicated by the potentially subtle differences associated with alterations in a single allele as well as by variations between individuals that arise from environmental or physiological factors. To circumvent these analytic problems, a method, named allele-specific differential expression analysis, was developed to compare the relative expression levels of two alleles of the same gene within the same cellular sample. The studies of allele-specific expression revealed that differential expression is relatively common in the human population.
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© 2005 Humana Press Inc., Totowa, NJ
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Yan, H. (2005). Snapshot of the Allele-Specific Variation in Human Gene Expression. In: Innocenti, F. (eds) Pharmacogenomics. Methods in Molecular Biology™, vol 311. Humana Press. https://doi.org/10.1385/1-59259-957-5:031
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DOI: https://doi.org/10.1385/1-59259-957-5:031
Publisher Name: Humana Press
Print ISBN: 978-1-58829-440-1
Online ISBN: 978-1-59259-957-8
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