Abstract
Intracellular Ca2+ ([Ca2+]i) can rise primarily via release from intracellular storage sites (e.g., the endoplasmic reticulum) or via entry across the membrane down the steep concentration gradient (1–3). Ca2+ can enter through two main classes of plasma membrane-located Ca2+ channels: receptor operated and voltage sensitive (4–7). Voltage-sensitive Ca2+ channels are involved in a wide and diverse array of physiological responses including neurotransmitter release (8). In addition, many guanine nucleotide protein (G) coupled receptors couple to voltage-sensitive Ca2+ channels to reduce Ca2+ influx (9,10).
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© 1999 Humana Press Inc., Totowa, NJ
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Hirota, K., Lambert, D.G. (1999). Measurement of [3H]PN200-110 and [125I]ω-Conotoxin MVIIA Binding. In: Lambert, D.G. (eds) Calcium Signaling Protocols. Methods in Molecular Biology™, vol 114. Humana Press. https://doi.org/10.1385/1-59259-250-3:149
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DOI: https://doi.org/10.1385/1-59259-250-3:149
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