Abstract
Gene targeting in mice has become a commonly used technique to elucidate gene function. The principles for the generation of such gene knockout mice are relatively straightforward and many of the experimental procedures are standardised (1–3). A further step toward increasing the efficiency in the generation of knockout mice lies in the pooling of resources and knowledge by establishing a centralized gene-targeting facility.
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© 2001 Humana Press Inc., Totowa, NJ
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Barnett, L.D., Köntgen, F. (2001). Gene Targeting in a Centralized Facility. In: Tymms, M.J., Kola, I. (eds) Gene Knockout Protocols. Methods in Molecular Biology, vol 158. Humana Press. https://doi.org/10.1385/1-59259-220-1:65
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DOI: https://doi.org/10.1385/1-59259-220-1:65
Publisher Name: Humana Press
Print ISBN: 978-0-89603-572-0
Online ISBN: 978-1-59259-220-3
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