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Peroxisomal β-oxidation enzymes

  • Part II Metabolic Functions
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Abstract

Peroxisomal fatty acid oxidation enzymes are summarized in comparison to their mitochondrial counterparts. The peroxisomal enzymes involved in the β-oxidation spiral are schematically classified into two groups. The first group consists of hitherto purified and characterized classical enzymes: palmitoyl-CoA oxidase, the L-bifunctional protein, and 3-ketoacyl-CoA. These enzymes are inducible and act on the straight chain substrates. The second group consists of recently identified enzymes, branched-chain oxidase, the d-bifunctional protein, and sterolcarrier protein x, which catalyze four reactions of β-oxidation cycle. These are noninducible and act on branched-chain substrates.

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  1. Takashi Hashimoto

    Present address: Department of Pathology, Northwestern University Medical School, 303 East Chicago Avenue, 60611, Chicago, IL

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  1. Department of Biochemistry, Shinshu University School of Medicine, Matsumoto, 390, Nagano, Japan

    Takashi Hashimoto

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Hashimoto, T. Peroxisomal β-oxidation enzymes. Cell Biochem Biophys 32, 63–72 (2000). https://doi.org/10.1385/CBB:32:1-3:63

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