Chest
Clinical Investigations: COPDClinical and Personality Profiles and Survival in Patients With COPD
Section snippets
MATERIALS AND METHODS
Sixteen male veterans with stable COPD regularly attending the Pulmonary Medicine Clinic at Syracuse (NY) Veterans Affairs (VA) Medical Center for many years were recruited for the study. All subjects had had routine laboratory and clinical investigations in the course of their treatment and no additional tests were obtained specifically for the purposes of this study.
Twenty-five consecutive FEV1 and FVC records were retrieved on the day of the recruitment and the rates of fall of these two
RESULTS
At the end of 4 years, nine subjects were alive (survivors) and seven died (nonsurvivors). All nonsurvivors died of respiratory failure and/or respiratory complications.
The values of selected variables in the two groups are shown in Table 2. Tables 3 and 4 summarize regularly used medications and concomitant illnesses other than COPD in the patients studied. The survivors and nonsurvivors were similar in the initial pulmonary function test results, age, duration of illness, and oxygen
DISCUSSION
Our results from this prospective double-blind study in patients with severe COPD show a significant difference in MMPI scores between those who died and those who were alive at the end of 4 years of follow-up irrespective of the degree of impairment in pulmonary function or oxygenation. A CS derived from easily obtained quantifiable objective data from the medical records also predicts mortality within 4 years with good reliability. The clinical and MMPI scores seem to be independent of each
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Abstract of this work was presented at the 61st Annual International Scientific Assembly of the American College of Chest Physicians, October 31, 1995.