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Journal of Shanxi Medical University. 2014, (05)

Effects of parathyroid hormone on quality of life in hemodialysis patientsChinese Full Text

LIU Dong;GAO Zhuo;WEI Xueming;LI Xinlun;HU Ruihai;LI Hongxia;MIAO Jing;LUN Lide;Department of Nephrology,Air Force General Hospital;Department of General Surgery,Air Force General Hospital;

Abstract: Objective To explore the effects of parathyroid hormone（ PTH） on health-related quality of life in uremic maintenance hemodialysis patients. Methods Eighty-eight uremic patients treated with hemodialysis were divided into three groups according to iPTH level:iPTH ＞ 800 pg / ml group（n = 31）,iPTH 300- 800 pg / ml group（n = 27）,iPTH 150- 299 pg / ml group（n = 30）. Healthrelated quality of life（ HRQOL） was estimated with the KDQOL-SFTMquestionnaire and score methods provided by Hays. Results The scores in iPTH ＞ 800 pg / ml and iPTH 300- 800 pg / ml groups were lower on the overall health rating（OHR）,symptom / problem list（SPL）,effects of kidney disease（EKD）,cognitive function（CF）,sleep,SF- 36,physical function（PF）,role-physical（RP）,body pain（BP）,vitality（VT）than those in iPTH150-299 pg/ml group（P ＜0.01 or P ＜0.05）. The scores were lower in iPTH ＞800 pg/ml group than in iPTH 300- 800 pg / ml group on PF,RP,and general health（GH）（P ＜ 0. 01 or P ＜ 0. 05）. Conclusion With the increase of parathyroid hormone,the quality of life decrease in uremic maintenance hemodialysis patients with secondary hyperparathyroidism.
Keywords：

hemodialysis; parathyroid hormone; quality of life;

  • DOI：

    10.13753/j.issn.1007-6611.2014.05.012

  • Series：

  • Subject：

  • Classification Code：

    R581.1;R692.5

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