In Vivo Administration of a JAK3 Inhibitor during Acute SIV Infection Leads to Significant Increases in Viral Load during Chronic Infection
Figure 3
The efficiency (% change from a mean of 3 baseline values) of depletion in the absolute numbers of CD3−, CD8α+, NKG2a+ (total NK cells) in the PBMC of control and the animals that received the JAK3 inhibitor as a function of time post infection is illustrated.
A) Shows the data with Means +/− SD and B) the Geometric means for the 2 groups of animals. The difference in the values at 2 weeks post infection in the 2 groups of animals was highly significant (p<0.0001).