IL-10-Producing Th1 Cells and Disease Progression Are Regulated by Distinct CD11c+ Cell Populations during Visceral Leishmaniasis
Figure 4
Autocrine IL-10 but not IL-27p28 regulates IL-12 and IL-10 production by cDCs.
(A) IL-12p70 and (B) IL-10 secretion was determined in cultures of cDCs sorted from d28 infected mice cultured with or without LPS and in the presence or absence of neutralizing mAbs to IL-10R or IL-27p28. Data are representative of 3 experiments. * = p<0.05, ** = p<0.01, *** = p<0.001.