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IFNγ Inhibits the Cytosolic Replication of Shigella flexneri via the Cytoplasmic RNA Sensor RIG-I

Figure 7

Inhibition of S. flexneri by RIG-I is partially dependent on the RNA polymerase III pathway.

Quantification of S. flexneri CFU in unstimulated or IFNγ-stimulated cells in the presence or absence of the RNA polymerase III inhibitor ML-60218 (20 µM). Data are representative of 3 independent experiments. *, p<0.05 (Student's t test).

Figure 7

doi: https://doi.org/10.1371/journal.ppat.1002809.g007