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Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response

Figure 10

B cell-intrinsic Myd88 regulates germinal center B cells but not CD4 T cell IFNγ expression.

Heterozygous mice (CD19-Cre/Myd88+/−) or mice with B cell specific deletion of Myd88 (CD19-Cre/Myd88flox/−) were infected with FV, At 14 dpi, splenocytes suspensions were analyzed by flow cytometry for GL7 expression in CD19+ B cells (A) and for IFNγ expression in CD4+, TCRβ+ T cells (B). Each bar represents the average of four mice.

Figure 10

doi: https://doi.org/10.1371/journal.ppat.1002293.g010