HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans
Figure 4
HapX positively regulates the levels of the CIR1 and RIM101 transcripts.
Quantification of HAPX, CIR1 and RIM101 transcripts by quantitative RT-PCR in WT, hapXΔ and cir1Δ strains under low-iron (top) and iron-replete (bottom) conditions. The data were normalized using 18S rRNA as an internal control and are presented as relative expression in comparison to the WT value set at 1. The data are from three biological and two technical replicates, and the bars represent standard deviations.