Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate
Figure 5
Temperature dependence of peptide-virus interaction.
(A) Inhibition of infectivity after incubating virus with DV2419–447 at various temperatures, as indicated. RT, room temperature. (B) Association of biotinyl-DV2419–447 (DV2B419–447) with purified dengue virions at 4°C and 37°C (see Methods).