Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes
Figure 1
Approximately 1×106 cells of each strain were plated on YPD media and E-test strips were placed on the media. The plates were incubated at 30°C for 72 h. Strains: H99 (wild type), H99R64 (resistant at 64 µg/ml of FLC), H99Rvt16, and H99Rvt26 (H99R64 derivatives obtained by daily transfer of H99R64 on drug-free media for 16 and 26 days, respectively).