Molecular Mechanisms of Ethanol-Induced Pathogenesis Revealed by RNA-Sequencing
Figure 2
Metabolic pathways affected by the presence of ethanol.
The numbers in parenthesis represent the ratio of the number of gene-specific mapped reads from the libraries obtained from cultures grown in ethanol and in the absence of ethanol. EtDh, ethanol dehydrogenase; acetalDh acetaldehyde dehydrogenase; ackA, acetate kinase; pta, phosphate transacetylase; acs, acetyl-CoA synthetase; ICDh, isocitrate dehydrogenase; ICL, isocitrate lyase; MDh, malate dehydrogenase; MQO, malate:quinone oxidoreductase; pckA, phosphoenolpyruvate carboxykinase; ppc, phosphoenolpyruvate carboxylase. Red and yellow arrows represent induced or repressed genes, respectively.