Virus Movements on the Plasma Membrane Support Infection and Transmission between Cells
Figure 1
Diffusional motions cover larger surface areas than directed drifts and confined motions.
Viruses have been observed to undergo three types of motion, random diffusion (cyan), retrograde drifts (also called retrograde flow, red), and confined motions (black) (see Table 1 and main text). (A and B) show the heterogeneity of two typical trajectories of adenovirus serotype 2 particles on human embryonic retinoblasts. The motion patterns were recorded by confocal microscopy at 25 Hz acquisition frequency and automatically classified by a machine-based learning algorithm [11]. Nonclassified motions are depicted in dark blue.