Molecular Evolutionary Consequences of Niche Restriction in Francisella tularensis, a Facultative Intracellular Pathogen
Figure 3
Likelihood estimates of dN/dS ratios across the Francisella phylogeny obtained using the software package Hyphy.
The analysis indicates statistically significant differences in dN/dS values for different tree branches. Different colors represent the maximum number of rate classes estimated from the data using the Akaike information criterion (AIC) with a genetic algorithm. Values on the branches represent local optima, with confidence intervals in brackets. To optimize the evolutionary models comparisons were separately optimized for the phylogeny of (A) F. tularensis strains, and (B) the Francisella genus, including F. philomiragia and F. novicida.