Naturally Occurring Lipid A Mutants in Neisseria meningitidis from Patients with Invasive Meningococcal Disease Are Associated with Reduced Coagulopathy
Figure 6
Clinical correlate of lpxL1 mutations in meningococcal meningitis.
(A) Frequency of rash in patients presenting with meningitis infected by lpxL1 wild-type and mutant strains. (B,C) Platelet counts on admission for lpxL1 wild-type and mutant strains (B) and patients presenting with and without rash (C). Horizontal bars reflect medians. The Mann-Whitney U test was used to identify differences between groups in continuous variables, and dichotomous variables were compared by the chi-square or Fisher exact test.