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A Legionella pneumophila Effector Protein Encoded in a Region of Genomic Plasticity Binds to Dot/Icm-Modified Vacuoles

Figure 1

High genomic plasticity in the region encoding lpg1965.

The Philadelphia1 genomic region flanking lpg1965 (pieC) was analyzed to obtain the specific genomic context of pieC. ORFs of novel translocated effectors are shown in black. Below is a low-resolution sequence alignment of this region, to scale, of all four sequenced genomes. Regions absent from the genomes of Lens, Paris and Corby are highlighted with grey bars.

Figure 1

doi: https://doi.org/10.1371/journal.ppat.1000278.g001