Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation
Figure 5
Dendritic cells are less activated in B. infantis-fed mice.
(A) The percentage of CD11c+MHC II+ mature dendritic cells staining positive for the co-stimulatory molecule CD80 are reduced in the Peyer's patch of B. infantis-fed mice prior to and during S. typhimurium infection. (B) Splenocyte dendritic cell CD80 expression is similar in both groups of un-infected mice but is significantly up-regulated with Salmonella infection only in the placebo group. *p<0.05 versus placebo, n = 6–9 animals per group per timepoint.