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Doxycycline Reduces Plasma VEGF-C/sVEGFR-3 and Improves Pathology in Lymphatic Filariasis

Figure 7

Plasma Levels of VEGF-C of Lymphedema Patients before and 12 Mo after Doxycycline Treatment

Plasma concentrations (mean ± SD) of VEGF-C were measured from plasma of lymphedema patients before and 12 mo after doxycycline treatment. The VEGF-C levels decreased significantly at 12 mo in the doxycycline-treated patients (p = 0.0499), in contrast to the placebo group (paired t-test).

Figure 7

doi: https://doi.org/10.1371/journal.ppat.0020092.g007