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Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice

Fig 3

mRNA levels of hypertrophy markers.

The hypertrophy marker genes Nppa (A), Nppb (B) and Acta1 (C) were upregulated by TAC and not different between Malat-1 WT and KO mice. (D) Malat-1 itself was not significantly deregulated after TAC. *p<0.05, **p<0.01, ***p<0.001 TAC versus Sham;$ $ $ $p<0.0001 KO versus WT.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0150236.g003