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Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease

Fig 6

Effect of 2DG treatment on cellular signaling pathways in vivo.

Measurements of phosphorylation levels of (A) AMPK, (B) ERK, (C) S6K, and (D) Akt using Western blot analysis in the kidneys of 10 week old +/+ and Cy/+ rats following 5-week treatment with 2DG or vehicle.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0146654.g006