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Activation of Kupffer Cells Is Associated with a Specific Dysbiosis Induced by Fructose or High Fat Diet in Mice

Fig 2

Analysis of hepatic phenotype and fat mass after 16 weeks of diet.

(A) Histological examination of liver tissue section stained with Hematoxylin-eosin (scale 50um). (B) Hepatic triglyceride content. (C) Fat mass of epididymal adipose tissue amount. (D) Liver / weight ratio. (E) Plasma ALT level. (F) Plasma AST level. Normal diet: ND; ND with fructose: ND/F; high fat diet: HFD; and HFD with fructose: HFD/F. Data represent the mean±SEM of 8 mice, *: p<0.05, **: p<0.01, ***p < 0.001.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0146177.g002