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Dysfunction of Liver Receptor Homolog-1 in Decidua: Possible Relevance to the Pathogenesis of Preeclampsia

Fig 5

Molecular expression mechanism underlying the effect of NR5A2 interference.

(A) Efficiency of NR5A2 siRNA mediated knockdown. (B) The mRNA expression of PRL and IGFBP1 after the knocking down of NR5A2. (C) The mRNA expression of WNT4 and BMP2 after the knocking down of NR5A2. (D) The mRNA expression of BMP2 and NR5A2 after the knocking down of BMP2. The data are expressed as the mean ± SEM. PRL, prolactin; IGFBP1, insulin-like growth factor binding protein 1; *P < 0.05; **P < 0.01; ***P < 0.001.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0145968.g005