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The Development of Macrophage-Mediated Cell Therapy to Improve Skeletal Muscle Function after Injury

Fig 8

Real-Time PCR evaluation of gene expression in gastrocnemius muscles 5 days post-reperfusion treated with saline or 2x106 M0 or M1 macrophages 24h after TK-I/R injury.

Gene expression of IGF-I (Igf1), CD206 (Mrc1) and PPAR-γ (PPARG) relative to saline. Values expressed as mean transcript values ± SEM; n = 3. 3- phosphoglycerate kinase (Pgk1) was used as internal reference gene. (*) p<0.05 compared to saline; (#) p<0.05 compared to M0D1, one-way ANOVA, Tukey-HSD post-hoc.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0145550.g008