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Methylated Host Cell Gene Promoters and Human Papillomavirus Type 16 and 18 Predicting Cervical Lesions and Cancer

Fig 2

HPV16 methylation status of 19 CpG sites in different regions of the viral genome.

N, normal cytology; I, LSIL/CIN1 diagnosis; II, LSIL/CIN2 diagnosis; III, HSIL/CIN3 diagnosis; CC, cervical cancer; SiHa, cervical cancer cell line; M, methylated; U, unmethylated; M+U, methylated and unmethylated with predominantly methylated DNA; U+M, methylated and unmethylated with predominantly unmethylated DNA.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0129452.g002