Visinets: A Web-Based Pathway Modeling and Dynamic Visualization Tool
Fig 6
Transient activation (tyrosine or serine/threonine phosphorylation) of EGFR and MAPK pathway components shown in Visinets using Plot function.
Each single iteration equates to the smallest incremental signal progression through the network (virtual time). R2—receptor dimer; Rp—phosphorylated receptor; RShP—Receptor-Shc-P; RShGS—Receptor-Shc-Grb-Sos complex; RafPP—phosphorylated raf1; MekPP—phosphorylated Mek1/2; ErkPP—phosphorylated Erk1/2.