Multivariate Dimensionality Reduction Approaches to Identify Gene-Gene and Gene-Environment Interactions Underlying Multiple Complex Traits
Figure 2
Comparison of statistical power between univarate GMDR method and GEE-GMDR under digenic, trigenic and tetragenic interaction models.
The horizontal axis represents different residual correlations. The empirical statistical power is defined as the proportion of significant true models at 5% level in 200 simulations.