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The Separatrix Algorithm for Synthesis and Analysis of Stochastic Simulations with Applications in Disease Modeling

Figure 1

The Separatrix Algorithm addresses two main sub-problems.

The first is to use observed binary outcomes (top) to estimate the probability of success (bottom), and the second is to choose new points to sample. This is done so as to identify a particular isocline, called the separatrix, as illustrated by the dashed gray line.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0103467.g001