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Host Competence and Helicase Activity Differences Exhibited by West Nile Viral Variants Expressing NS3-249 Amino Acid Polymorphisms

Figure 4

Viremia profiles of AMCRs inoculated with WN/IC NS3-249 mutants.

(A) Mean daily viremias from AMCRs (n = 8) from Colorado inoculated with WN/IC NS3-249 point mutants (NS3-249P, 249D, 249T, 249H, and 249A); (B) Mean daily viremias from 2012 captured AMCRs (n = 4) inoculated with WN/IC NS3-249P and 249N mutants. Bars denote standard deviations from the mean.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0100802.g004