Effects of Prolonged Exposure to Hypobaric Hypoxia on Oxidative Stress, Inflammation and Gluco-Insular Regulation: The Not-So-Sweet Price for Good Regulation
Figure 1
Gluco-insulin axis regulation in members of the research team reaching the summit (•) or remaining at base camp (○) during the expedition.
Homeostatic model of assessment was calculated as a proxy indicator of systemic insulin resistance (HOMA-IR). C-Peptide/Insulin Ratio was calculated as a measure of hepatic insulin extraction. Median data are presented for the two groups (lines) and all subjects (bars). Error bars are 25th and 75th percentiles. Significant differences were flagged in each graph: ***p<0.001. No significant differences were observed between climbers and base camp at either time point.