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Mouse Models for Pseudoxanthoma Elasticum: Genetic and Dietary Modulation of the Ectopic Mineralization Phenotypes

Figure 3

Immunofluorescence staining of Abcc6 in the liver of mice.

Note positive staining associated with the plasma membranes in C57BL/6J mice (arrowheads) and complete absence of the staining in Abcc6−/− mice. A low, yet detectable level of immunofluorescence was noted in the four other strains which harbor the A allele of the Abcc6 gene.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0089268.g003