Aberrant Methylation of Gene Associated CpG Sites Occurs in Borderline Personality Disorder
Figure 3
Methylation analysis of APBA2, APBA3, GATA4, HLCS, KCNQ1, MCF2, NINJ2 and TAAR5 by bisulfite pyrosequencing.
PCR products obtained from three independent bisulfite treated DNA of female BPD patients (n=9) and controls (n=8) were analyzed. Average methylation levels ± SD of individual CpG sites from three independent pyrosequencing reactions are indicated and summarized for all CpGs. Significant p-values are indicated (two-tailed t-test).