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Senescence of Primary Amniotic Cells via Oxidative DNA Damage

Figure 1

wsCSE induces increased ROS levels in primary amnion cells.

Preincubation with the antioxidant N-acetyl cysteine (NAC) prevented ROS accumulation (n = 8). Controls – Untreated amnion cells in culture. Data were significant (p<0.05) for all time points for wsCSE treated cells compared to both control and wsCSE+NAC treated amnion cells.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0083416.g001