Quantitative Identification of Mutant Alleles Derived from Lung Cancer in Plasma Cell-Free DNA via Anomaly Detection Using Deep Sequencing Data
Figure 3
Temporal changes of EGFR mutations in plasma DNA from patients with three or more samples.
Each dot represents a time point of sampling. The diagram is not precise representation of time scale, and only the order of dots is valid information. Figures represent EGFR mutations in 10,000 sequence reads: black, exon 19 deletion; blue, L858R; red, T790M. Only figures exceeding the thresholds are shown. “Mutation type” indicates that in the biopsy samples.