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Hormonal Regulation of MicroRNA Expression in Steroid Producing Cells of the Ovary, Testis and Adrenal Gland

Figure 2

MicroRNA (miRNA) expression profiles in adrenals from rats treated with ACTH, 17α-E2, DEX or saline (control).

[A]. The heat map represents the expression levels of 45 miRNAs in two conditions (control and ACTH). [B, C]. The heat map represents the expression levels of 163 miRNAs in two conditions (control and 17α-E2). 74 miRNAs were up-regulated [B] and 89 miRNAs were down-regulated with 17α-E2 [C]. [D]. The heat map represents the expression levels of 33 miRNAs in two conditions (control and DEX). Red, up-regulated genes; blue, down-regulated genes.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0078040.g002