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Novel Polyfermentor Intestinal Model (PolyFermS) for Controlled Ecological Studies: Validation and Effect of pH

Figure 1

Setup and design of the Polyfermentor Intestinal Model (PolyFermS).

Control (CR) and test reactors (TR) were continuously inoculated with effluents from inoculum reactors (IR) containing 30% (v/v) of fecal beads from donors A (model A), B (model B) and C (model C), respectively. Metabolites were quantified daily by HPLC analysis. Community structure was studied by HITChip analyses at selected time points t1, t2, t3 and t4. RT, mean retention time.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0077772.g001